How is Eagle-Barrett syndrome primarily diagnosed?

Eagle-Barrett syndrome, also known as prune belly syndrome, is primarily diagnosed through radiographic studies, including abdominal X-rays (AXR). This syndrome is characterized by a triad of findings: abdominal wall defects, undescended testicles, and urinary tract abnormalities. The use of radiographic imaging helps in assessing the extent of the abdominal wall defects and any associated renal abnormalities, which are critical for confirming the diagnosis.

While other methods like physical examinations and genetic testing can provide supportive information, they do not typically establish the diagnosis of Eagle-Barrett syndrome on their own. Physical examinations might identify external features suggestive of the syndrome, but imaging is essential for visualizing internal organ involvement. Genetic testing may reveal mutations, but the diagnosis relies more heavily on the physical observations made during imaging studies. Blood tests generally do not provide direct evidence for this condition, making radiographic assessment the most vital tool for diagnosis.