In ROP, what do the zones describe?

The zones in Retinopathy of Prematurity (ROP) describe the location of the disease within the retina. ROP is classified based on the anatomical areas of the retina affected, which are categorized into three distinct zones. Zone I is the area around the optic nerve and includes the most central part of the retina, while Zone II encompasses a larger area extending toward the peripheral retina, and Zone III involves the peripheral retina. This zonal classification is crucial for clinicians as it helps in assessing the extent of the disease and planning appropriate monitoring and intervention.

While the severity of the disease is assessed through different criteria, such as the presence of certain characteristics like plus disease, the zones specifically indicate which parts of the retina are affected. Treatment options can vary based on the severity and extent of ROP, but they are not directly described by the zones themselves. The infant’s age can impact the risk of developing ROP and the approach to treatment, but it is not what the zones are intended to describe. Understanding these zones is key for effective management and treatment planning in infants at risk for ROP.