What is a key characteristic of every newborn related to pulmonary vascular resistance (PVR) and PPHN?

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A key characteristic of every newborn related to pulmonary vascular resistance (PVR) and persistent pulmonary hypertension of the newborn (PPHN) is the increased risk for developing PPHN. This condition occurs when high levels of PVR persist after birth, leading to altered blood flow and oxygenation in the newborn.

In the transition from fetal to extrauterine life, there is a natural decrease in PVR as the lungs expand with air and begin to function, but some newborns, particularly those with underlying conditions, may fail this transition, leading to PPHN. This is significant because it highlights the vulnerability of newborns to conditions that can impact their respiratory and cardiovascular systems right after birth.

Understanding that all newborns are at some risk for PPHN emphasizes the importance of careful monitoring and early recognition of symptoms that may indicate elevated PVR or related complications. Recognizing this risk is crucial for timely intervention and management of affected newborns.

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