Which clinical manifestation is commonly seen in early onset GBS infection?

Apnea is a frequently observed clinical manifestation in early onset Group B Streptococcus (GBS) infection. This condition is characterized by pauses in breathing that can last for more than 20 seconds or shorter pauses associated with bradycardia or oxygen desaturation. In neonates, especially those with GBS infection, apnea is often a result of respiratory distress or an immature central nervous system, leading to irregularities in respiratory control.

Early onset GBS infection typically occurs within the first week of life and can present with various symptoms, including respiratory distress, lethargy, and poor feeding. Apnea is particularly concerning and can indicate a significant underlying infection or functional impairment.

Other potential clinical manifestations that may be considered in the context of infections, analysis of the context or population is crucial to assess relevance. However, apnea remains a hallmark sign in the diagnosis and monitoring of early onset GBS infections. Understanding these clinical signs is essential for early identification and management of affected infants in the neonatal intensive care setting.