Which of the following can be a genetic association with duodenal atresia?

Duodenal atresia is commonly associated with certain genetic conditions, with Down syndrome being one of the most well-known associations. This link is largely attributed to the chromosomal abnormalities present in Down syndrome, specifically an extra copy of chromosome 21. Infants with Down syndrome often exhibit a variety of congenital anomalies, including gastrointestinal obstructions like duodenal atresia. The increased prevalence of duodenal atresia in these patients reflects the complex interactions of genetic factors that impact development.

Other conditions, while they present their own set of congenital challenges, do not have the same strong association with duodenal atresia as Down syndrome does. Understanding these associations helps in early identification and management of affected newborns in a neonatal intensive care setting.