Which of the following is NOT a feature of Beckwith-Wiedemann Syndrome?

In the context of Beckwith-Wiedemann Syndrome (BWS), it is essential to understand the hallmark features associated with this condition. BWS is characterized by a variety of anatomical and metabolic features, one of which is macrosomia, meaning individuals with the syndrome are typically larger than average for their gestational age. Macroglossia, or an enlarged tongue, is another common feature, often leading to feeding difficulties or respiratory issues.

Ear creases can also be associated with BWS, although they are not one of the defining features and may be present in a subset of patients. However, the presence of oligohydramnios, which refers to a condition of decreased amniotic fluid, is not typically linked with BWS. In fact, individuals with this syndrome often experience increased amniotic fluid levels (polyhydramnios) due to their macrosomia and other factors.

Thus, the lack of a direct association between oligohydramnios and the core characteristics of Beckwith-Wiedemann Syndrome makes it the correct answer in identifying a feature that is NOT consistent with this condition.